Transitions In Depression

Personalized early warning signals - Mapping psychological changes

THE RESEARCH

The aim of the TRANS-ID project (TRANSitions In Depression) is to discover personalised signals that may indicate critical transitions in psychological symptoms. We will investigate within single individuals which early warning signals precede symptom change and thereby examine whether psychological symptoms behave according to the principles of complex dynamical systems.

To gain insight into this, we use a diary approach (also known as the experience sampling method) to capture the micro-level changes of symptoms, emotions, behaviours and daily context over time. In addition, we collect measurements of movement and heart rate using high-tech, user-friendly sensors.

The project is divided into three sub-projects:

  • TRANS-ID TAPERING

    This project investigates what kind of changes occur during the tapering of antidepressant medication, and whether early warning signals precede the moment that depressive symptoms increase. We are recruiting from a population of people who previously experienced depressive symptoms, and who wish to taper their antidepressants. Read more...

  • TRANS-ID RECOVERY

    This project investigates whether we can anticipate the moment individuals begin to recover from depressive symptoms. We are recruiting from a population of people who are currently experiencing depressive symptoms and are going to follow psychological treatment. Read more...

  • TRANS-ID TRAILS

    In this project, we aim to find out whether we can anticipate what kind of changes young adults with an increased risk for psychopathology experience in terms of mental health problems. We investigate this in a population of young adults because early adulthood is a critical life period during which many changes occur that may influence the development of mental health issues. Read more...

CLINICAL RELEVANCE

We expect that this project could result in a big leap forward in the field of psychopathology research and will aid in developing knowledge that is relevant to the individual patient with mental health problems. If transitions in depressive symptoms indeed behave according to complex dynamical system principles, this would mean that there is an alternative route to getting precise and person-specific information on 1) likelihood and timing of transitions to new episodes of psychological symptoms and 2) readiness for change.

Taking part in the TRANS-ID research projects may also have direct advantages for participants It may give them insights into which signals indicate a shift in symptoms, and how their symptoms fluctuate. At the end of the daily diary period we create a personal report for each participant that shows their answers over time.

Two of the three sub-projects are currently recruiting (Dutch-speaking) participants: TRANS-ID Recovery and TRANS-ID Tapering. If you wish to get in touch, or stay up-to-date about the development of a particular research project, select one of the project sub-pages.

TRANS-ID

Tapering

Transitions in Depressive Symptoms during tapering of antidepressants.

TRANS-ID

Recovery

Transitions in Depressive Symptoms during psychological treatment.

TRANS-ID

TRAILS

Changes in mental health studied in a high-risk young adult population.

NEWS

TRANS-ID research starts recruitment!

As of May 1st 2017 the TRANS-ID project has officially started. People can now sign up for participation in the TRANS-ID Tapering and TRANS-ID Recovery projects. Continue reading...

Interview: Marieke Wichers

Op 6 december 2016 hield Marieke Wichers, hoogleraar Dynamiek van emotieregulatie en psychopathologie bij het ICPE (RUG) haar oratie met als titel “Durven zoeken in het donker; op weg naar een kantelpunt in de psychiatrie”. Continue reading...

Radio-interview: Op zoek naar het kantelpunt in de psychiatrische patiënt

Is er een kans dat u een psychiatrische stoornis ontwikkelt? En zo ja, is dan te voorspellen wanneer er weer verbetering optreedt? Hoogleraar Marieke Wichers gaat de symptomen van stoornissen live volgen om dat uit te zoeken. Continue reading...

OUR VISION

Our research is anchored in the following principles:

Psychopathology is not static but dynamic.

Therefore, we aim to map the complete processes of symptom change in detail.

Psychopathology moves across diagnostic boundaries.

From this perspective, we investigate changes in mental health symptomatology.

Research should yield results that are relevant to the individual.

This is why we designed this project to allow the analysis of person-specific models.

CONTACT

info@transid.nl

TRANS-ID Tapering

Tel: 050 - 361 9005

TRANS-ID Recovery

Tel: 050 - 361 3864

TRANS-ID TRAILS

Tel: 050 - 361 7289

Movement and Heart Rate Measurements

Tel: 050 - 361 3864

This project is supported by

Universitair Medisch Centrum Groningen
Rijksuniversiteit Groningen
European Research Council